GSK3B
Sign in to saveAlso known as 7330414F15Rik, 8430431H08Rik, C86142, GSK-3, GSK-3beta, GSK3, glycogen synthase kinase 3 beta
protein-coding gene in the species Homo sapiens
Gene data
GSK3B- Name
- glycogen synthase kinase 3 beta
- Type
- protein-coding
- Position
- 119,821,321–120,095,712 (−)
- Ensembl
- ENSG00000082701
- RefSeq RNA
- NM_001146156.2, NM_001354596.2, NM_002093.4, XM_006713610.4, XM_054346384.1
- RefSeq protein
- NP_001139628.1, NP_001341525.1, NP_002084.2, XP_006713673.1, XP_054202359.1
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
ErbB signaling pathway - Homo sapiens (human)Chemokine signaling pathway - Homo sapiens (human)Cell cycle - Homo sapiens (human)mTOR signaling pathway - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)Wnt signaling pathway - Homo sapiens (human)Hedgehog signaling pathway - Homo sapiens (human)Axon guidance - Homo sapiens (human)Hippo signaling pathway - Homo sapiens (human)Focal adhesion - Homo sapiens (human)
via MyGene.info
Gene · Ensembl
glycogen synthase kinase 3 beta
- Symbol
- GSK3B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:119,821,321-120,095,712
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI