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umbellulone

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EntityQ7881242· pop 8· linked from 286 articles

umbellulone

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Also known as 3-thujen-2-one, 4-methyl-1-propan-2-ylbicyclo[3.1.0]hex-3-en-2-one

Umbellulone is a headache-inducing monoterpene ketone found in the leaves of the tree Umbellularia californica, sometimes known as the "headache tree".

Chemical data

Formula
C10H14O
Molecular weight
150.22 g/mol
IUPAC name
4-methyl-1-propan-2-ylbicyclo[3.1.0]hex-3-en-2-one

via PubChem

Wikidata facts

Mass
150.104465
Show 3 more facts
chemical formula
C₁₀H₁₄O
canonical SMILES
CC1=CC(=O)C2(C1C2)C(C)C
Commons category
Umbellulone
Sources (2)

via Wikidata · CC0

~7 min read

Article

10 sections
Contents
  • History
  • Structure and reactivity
  • Synthesis
  • Mechanism of action
  • TRPA1
  • TRPM8
  • Toxicity
  • Other applications
  • References
  • Further reading

Umbellulone is a headache-inducing monoterpene ketone found in the leaves of the tree Umbellularia californica, sometimes known as the "headache tree".

It is hypothesized to cause headaches by influencing the trigeminovascular system via TRPA1.

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