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GeneQ18032305· pop 5· linked from 12 articles

USF2

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Also known as FIP, bHLHb12, upstream transcription factor 2, c-fos interacting

Upstream stimulatory factor 2 is a protein that in humans is encoded by the USF2 gene.

Gene data

USF2

Name: upstream transcription factor 2, c-fos interacting
Type: protein-coding
Position: 35,268,485–35,279,821 (+)
Aliases: FIP, bHLHb12
Ensembl: ENSG00000105698
RefSeq RNA: NM_001321150.2, NM_003367.4, NM_207291.3, XM_005259197.5, XM_011527260.3
RefSeq protein: NP_001308079.1, NP_003358.1, NP_997174.1, XP_005259254.1, XP_011525562.1

This gene encodes a member of the basic helix-loop-helix leucine zipper family of transcription factors. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes. [provided by RefSeq, Mar 2016].

Gene Ontology

Biological process

regulation of transcription by RNA polymerase II glucose mediated signaling pathway glucose mediated signaling pathway glucose mediated signaling pathway glucose mediated signaling pathway late viral transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II

Molecular function

RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding

Cellular component

chromatin nucleus nucleus nucleus nucleoplasm nucleoplasm

Pathways

Signal Transduction ESR-mediated signaling Signaling by Nuclear Receptors Estrogen-dependent gene expression Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)

via MyGene.info

Gene · Ensembl

upstream transcription factor 2, c-fos interacting

Symbol: USF2
Biotype: Protein coding
Organism: Homo sapiens
Location: 19:35,268,485-35,279,821
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 2527
exact match: identifiers.org/ncbigene/7392
found in taxon: Homo sapiens
genomic start: 35268962
chromosome: human chromosome 19
genomic end: 35770724
cytogenetic location: 19q13.12

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

6 sections

Contents

Function
Interactions
Regulation
References
Further reading
External links

Upstream stimulatory factor 2 is a protein that in humans is encoded by the USF2 gene.

== Function ==

Excerpted from Wikipedia’s “USF2” article, available under the CC BY-SA 4.0 licence.

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via Wikidata sitelinks · CC0