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ProteinQ6587033· pop 13· linked from 211 articles

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Also known as Vitronectin, serum spreading factor, V75, epibolin, S-protein, VTN, complement S-protein, Serum-spreading factor

Vitronectin (VTN or VN) is a glycoprotein of the hemopexin family which is synthesized and excreted by the liver, and abundantly found in serum, the extracellular matrix and bone. In humans it is encoded by the VTN gene.

Protein · UniProt

Vitronectin

Gene
VTN
Organism
Homo sapiens (Human)
Length
478 aa
Molecular mass
54,306 Da
Evidence
1: Evidence at protein level

Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway

3D-structureCell adhesionDirect protein sequencingDisulfide bondGlycoproteinHeparin-bindingPhosphoproteinProteomics identification
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Swiss-Prot (reviewed) · via UniProt

Research

6,206 papers

via PubMed

Clinical Trials

22 registered

via ClinicalTrials.gov

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