YWHAQ
Sign in to saveAlso known as 14-3-3, 1C5, HS1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
14-3-3 protein theta is a protein that in humans is encoded by the YWHAQ gene.
Gene data
YWHAQ- Name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
- Type
- protein-coding
- Position
- 9,583,334–9,639,472 (−)
- Aliases
- 14-3-3, 1C5, HS1
- Ensembl
- ENSG00000134308
- RefSeq RNA
- NM_006826.4
- RefSeq protein
- NP_006817.1
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
- Symbol
- YWHAQ
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:9,583,334-9,639,472
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein YWHAQ PDB 2btp.png
Show 8 more facts
- HomoloGene ID
- 105677
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10971
- genomic end
- 9630997
- genomic start
- 9583967
- chromosome
- human chromosome 2
- cytogenetic location
- 2p25.1
- expressed in
- Human penis
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
14-3-3 protein theta is a protein that in humans is encoded by the YWHAQ gene.
== Function ==
Excerpted from Wikipedia’s “YWHAQ” article, available under the CC BY-SA 4.0 licence.