ZFYVE1

Also known as DFCP1, PPP1R172, SR3, TAFF1, ZNFN2A1, zinc finger FYVE-type containing 1

Zinc finger FYVE domain-containing protein 1 is a protein that in humans is encoded by the ZFYVE1 gene.

In the Vinony graph

Within Vinony's link graph, ZFYVE1 is referenced by 3 other articles, and connects out to PubMed, human chromosome 14 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 14.

Its subject is documented across 6 Wikipedia language editions.

Gene data

ZFYVE1

Name: zinc finger FYVE-type containing 1
Type: protein-coding
Position: 72,969,445–73,027,140 (−)
Aliases: DFCP1, PPP1R172, SR3, TAFF1, ZNFN2A1
Ensembl: ENSG00000165861
RefSeq RNA: NM_001281734.2, NM_001281735.1, NM_021260.4, NM_178441.2, XM_017021373.2
RefSeq protein: NP_001268663.1, NP_001268664.1, NP_067083.1, NP_848535.1, XP_016876862.1

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].

Pathways

Autophagy - animal - Homo sapiens (human)Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

via MyGene.info

Gene · Ensembl

zinc finger FYVE-type containing 1

Symbol: ZFYVE1
Biotype: Protein coding
Organism: Homo sapiens
Location: 14:72,969,445-73,027,140
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 10945
exact match: identifiers.org/ncbigene/53349
found in taxon: Homo sapiens
genomic end: 73027131
genomic start: 73436159
chromosome: human chromosome 14
cytogenetic location: 14q24.2

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

2 sections

Contents

References
Further reading

Zinc finger FYVE domain-containing protein 1 is a protein that in humans is encoded by the ZFYVE1 gene.

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.

Excerpted from Wikipedia’s “ZFYVE1” article, available under the CC BY-SA 4.0 licence.