ZNF331

Also known as RITA, ZNF361, ZNF463, zinc finger protein 331

Zinc finger protein 331 is a protein that in humans is encoded by the ZNF331 gene.

In the Vinony graph

Within Vinony's link graph, ZNF331 is referenced by 2 other articles, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 19.

Its subject is documented across 6 Wikipedia language editions.

Gene data

ZNF331

Name: zinc finger protein 331
Type: protein-coding
Position: 53,519,527–53,580,271 (+)
Aliases: RITA, ZNF361, ZNF463
Ensembl: ENSG00000130844
RefSeq RNA: NM_001079906.2, NM_001079907.1, NM_001253798.2, NM_001253799.2, NM_001253800.3
RefSeq protein: NP_001073375.1, NP_001073376.1, NP_001240727.1, NP_001240728.1, NP_001240729.1

This gene encodes a zinc finger protein containing a KRAB (Kruppel-associated box) domain found in transcriptional repressors. This gene may be methylated and silenced in cancer cells. This gene is located within a differentially methylated region (DMR) and shows allele-specific expression in placenta. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2015].

Gene Ontology

Biological process

regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II

Molecular function

RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific protein binding zinc ion binding

Cellular component

nucleus nucleus

Pathways

Herpes simplex virus 1 infection - Homo sapiens (human)Epigenetic regulation of gene expression Epigenetic regulation of gene expression Generic Transcription Pathway RNA Polymerase II Transcription Gene expression (Transcription)Gene expression (Transcription)Regulation of endogenous retroelements Regulation of endogenous retroelements Regulation of endogenous retroelements by KRAB-ZFP proteins

via MyGene.info

Gene · Ensembl

zinc finger protein 331

Symbol: ZNF331
Biotype: Protein coding
Organism: Homo sapiens
Location: 19:53,519,527-53,580,271
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 41276
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/55422
chromosome: human chromosome 19
genomic start: 53519527
genomic end: 54083523
cytogenetic location: 19q13.42

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Zinc finger protein 331 is a protein that in humans is encoded by the ZNF331 gene.

Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form one family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM]

Excerpted from Wikipedia’s “ZNF331” article, available under the CC BY-SA 4.0 licence.