ZNF346
Sign in to saveAlso known as JAZ, Zfp346, zinc finger protein 346
Zinc finger protein 346 is a protein that in humans is encoded by the ZNF346 gene.
Gene data
ZNF346- Name
- zinc finger protein 346
- Type
- protein-coding
- Aliases
- JAZ, Zfp346
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8073
- exact match
- identifiers.org/ncbigene/23567
- genomic end
- 176508190
- genomic start
- 176449697
- cytogenetic location
- 5q35.2
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Zinc finger protein 346 is a protein that in humans is encoded by the ZNF346 gene.
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival.