Anatomical pathology

a magnifying system capable of showing the interior or surface of a microscopic object by means of directed electron beams

An autopsy (also referred to as post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death; or the exam may be performed to evaluate any disease or injury that may be present for research or educational purposes. The term necropsy is generally used for non-human animals.

thumb|Squamous cell carcinoma occluding bronchus, with lymph node metastasis

A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, which may be called a tumour or tumor.

Atrophy is the partial or complete wasting away of a part of the body. Causes of atrophy include mutations (which can destroy the gene to build up the organ), poor nourishment, poor circulation, loss of hormonal support, loss of nerve supply to the target organ, excessive amount of apoptosis of cells, and disuse or lack of exercise or disease intrinsic to the tissue itself. In medical practice, hormonal and nerve inputs that maintain an organ or body part are said to have trophic effects. A diminished muscular trophic condition is designated as atrophy. Atrophy is reduction in size of cell, or

permanent, irreversible, total cessation of brain function

An adenoma is a benign tumor of epithelial tissue with glandular origin, glandular characteristics, or both. Adenomas can grow from many glandular organs, including the adrenal glands, pituitary gland, thyroid, prostate, and others. Some adenomas grow from epithelial tissue in nonglandular areas but express glandular tissue structure (as can happen in familial polyposis coli). Although adenomas are benign, they should be treated as pre-cancerous. Over time adenomas may transform to become malignant, at which point they become adenocarcinomas. Most adenomas do not transform. However, even thoug

In anatomy, a fistula (: fistulas or fistulae ; from Latin fistula, "tube, pipe") is an abnormal connection (i.e. tube) joining two hollow spaces (technically, two epithelialized surfaces), such as blood vessels, intestines, or other hollow organs to each other, often resulting in an abnormal flow of fluid from one space to the other.

A sarcoma is a rare type of cancer that arises from cells of mesenchymal origin. Originating from mesenchymal cells means that sarcomas are cancers of connective tissues such as bone, cartilage, muscle, fat, or vascular tissues.

Hypertrophy is an increase in the size of individual cells. In multicellular organisms, growth is typically achieved through a combination of this cellular enlargement and hyperplasia, which is an increase in the number of cells. While distinct processes, they often occur concurrently. Hypertrophy can lead to a relative increase in the volume of a tissue or organ, and contributes to the overall growth of an organism. In organisms characterized by eutely, where the total number of somatic cells is fixed upon reaching maturity, post-embryonic growth is achieved almost exclusively through hypertr

Hyperplasia (from ancient Greek ὑπέρ huper 'over' + πλάσις plasis 'formation'), or hypergenesis, is an enlargement of an organ or tissue caused by an increase in the amount of organic tissue that results from cell proliferation. It may lead to the gross enlargement of an organ, and the term is sometimes confused with benign neoplasia or benign tumor.

A granuloma is an aggregation of macrophages (along with other cells) that forms in response to chronic inflammation. This occurs when the immune system attempts to isolate foreign substances that it is otherwise unable to eliminate. Such substances include infectious organisms including bacteria and fungi, as well as other materials such as foreign objects, keratin, and suture fragments.

medical specialty

A lesion is any damage or abnormal change in the tissue of an organism, usually caused by injury or diseases. The term lesion is derived from the Latin , meaning "injury". Lesions may occur in plants and animals.

thumb|230px|Main staining patterns on chromogenic immunohistochemistry. thumb|right|Immunofluorescence of human skin using an anti-IgA antibody. The skin is from a patient with [[Henoch–Schönlein purpura: IgA deposits are found in the walls of small superficial capillaries (yellow arrows). The pale wavy green area on top is the epidermis, the bottom fibrous area is the dermis.]] thumb|"Block" staining: strong nuclear and cytoplasmic expression in a continuous segment of cells. Immunohistochemistry is a form of immunostaining. It involves the process of selectively identifying antigens in cells

thumb|right|350px|Micrograph|Microscope image showing [[contraction band necrosis, a histopathologic finding of myocardial infarction (heart attack).]] Histopathology (compound of three Greek words: 'tissue', 'suffering', and -logia 'study of') is the microscopic examination of tissue in order to study the manifestations of disease. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy or surgical specimen by a pathologist, after the specimen has been processed and histological sections have been placed onto glass slides. In contrast, cytopathology examines f

classification in immunology

genetic testing technique

thumb|278x278px|Vasculature of porcine skin under fluorescence ([[Smooth muscle actin with AlexaFluor 488). Green = smooth muscle actin (SMA) with Alexa 488 fluorophore. Blue = DAPI counterstain. Red = auto-fluorescence. ]]

A hamartoma is a mostly benign, local malformation of cells that resembles a neoplasm of local tissue but is usually due to an overgrowth of multiple aberrant cells, with a basis in a systemic genetic condition, rather than a growth descended from a single mutated cell (monoclonality), as would typically define a benign neoplasm/tumor. Despite this, many hamartomas are found to have clonal chromosomal aberrations that are acquired through somatic mutations, and on this basis the term hamartoma is sometimes considered synonymous with neoplasm. Hamartomas are by definition benign, slow-growing o

Rhabdomyosarcoma (RMS) is a highly aggressive form of cancer that develops from mesenchymal cells that have failed to fully differentiate into myocytes of skeletal muscle. Cells of the tumor are identified as rhabdomyoblasts.

thumb|Micrograph of a [[vasculitic neuropathy. Plastic embedded. Toluidine blue stain.]] Neuropathology is the study of disease of nervous system tissue, usually in the form of either small surgical biopsies or whole-body autopsies. Neuropathologists usually work in a department of anatomic pathology, but work closely with the clinical disciplines of neurology, and neurosurgery, which often depend on neuropathology for a diagnosis. Neuropathology also relates to forensic pathology because brain disease or brain injury can be related to cause of death. Neuropathology should not be confused with

thumb|alt=Chest X-ray showing pulmonary hypoplasia|Pulmonary hypoplasia

medical condition

solid, non-blisterform elevated areas in or under the skin

A leiomyoma, also known as a fibroid, is a benign smooth muscle tumor that very rarely becomes cancer (0.1%). They can occur in any organ, but the most common forms occur in the uterus, small bowel, and the esophagus. Polycythemia may occur due to increased erythropoietin production as part of a paraneoplastic syndrome.

thumb|A pair of micrographs of a cytopathology specimen showing a 3-dimensional cluster of cancerous cells ([[serous carcinoma)]] thumb|An adenocarcinoma with typical features as can be seen on cytopathology

skin carcinoma that has material basis in squamous cells

new tissue that forms on a wound's surface

process of determining the extent to which a cancer has developed by spreading

emerging discipline within pathology that analyses disease-causing factors at the DNA and RNA level

In medicine, prolapse is a condition in which organs fall down or slip out of place. It is used for organs protruding through the vagina, rectum, or for the misalignment of the valves of the heart. A spinal disc herniation is also sometimes called "disc prolapse". Prolapse means "to fall out of place", from the Latin '''' meaning "to fall out".

benign neuroma of an intermetatarsal plantar nerve

sub-specialty of pathology that focuses on determining the cause of death by examining a corpse

arteriovenous malformation that is located in the brain

human disease

benign bone tumor that arises from osteoblasts and was originally thought to be a smaller version of an osteoblastoma

in the blood

disruption of the joint between the tibia and the femur

group of disorders

human disease

human disease

brain cancer that is usually located in the brain, but can occur anywhere in the central nervous system

medical procedure that blocks blood supply to uterine fibroids

Osteoblastoma is an uncommon osteoid tissue-forming primary neoplasm of the bone.

thumb|upright|Main staining types when using H&E stain|hematoxylin and eosin (H&E). thumb|upright|A basophil granulocyte is surrounded by lightly staining eosinophilic [[erythrocytes in an H&E staining.]]

Choristomas, a form of heterotopia, are masses of normal tissues found in abnormal locations. In contrast to a neoplasm or tumor, the growth of a choristoma is normally regulated.

medical condition

human disease

medical condition

staging scale of lymphomas

human disease

Human disease

healing from bone injury

mammalian protein found in Homo sapiens

medical condition

medical condition

family of related stains for examination of blood including the detection of parasites