EC 3.5.1

Ureases (), functionally, belong to the superfamily of amidohydrolases and phosphotriesterases. Ureases are found in numerous Bacteria, Archaea, fungi, algae, plants, and some invertebrates. Ureases are nickel-containing metalloenzymes of high molecular weight. Ureases are important in degrading avian faecal matter, which is rich in uric acid, the breakdown product of which is urea, which is then degraded by urease as described here.

Asparaginase is an enzyme that is used as a medication and in food manufacturing. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL). It is given by injection into a vein, or muscle. A PEGylated version, pegaspargase, is also available. In food manufacturing it is used to decrease acrylamide.

class of enzymes

In enzymology, an amidase (, acylamidase, acylase (misleading), amidohydrolase (ambiguous), deaminase (ambiguous), fatty acylamidase, N-acetylaminohydrolase (ambiguous)) is an enzyme that catalyzes the hydrolysis of an amide. In this way, the two substrates of this enzyme are an amide and H2O, whereas its two products are monocarboxylate and NH3.

Glutaminase (, glutaminase I, L-glutaminase, glutamine aminohydrolase) is an amidohydrolase enzyme that generates glutamate from glutamine. Glutaminase has tissue-specific isoenzymes. Glutaminase has an important role in glial cells.

mammalian protein found in Homo sapiens

mammalian protein found in Homo sapiens

Histone deacetylase 1 (HDAC1) is an enzyme that in humans is encoded by the HDAC1 gene.

Histone deacetylase 4, also known as HDAC4, is a protein that in humans is encoded by the HDAC4 gene.

Histone deacetylase 7 is an enzyme that in humans is encoded by the HDAC7 gene.

Ceramidase (, acylsphingosine deacylase, glycosphingolipid ceramide deacylase) is an enzyme which cleaves fatty acids from ceramide, producing sphingosine (SPH) which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate (S1P).

class of enzymes

Histone deacetylase 9 is an enzyme that in humans is encoded by the HDAC9 gene.

Biotinidase (, amidohydrolase biotinidase, BTD), also known as biotinase, is an enzyme that in humans is encoded by the BTD gene.

protein-coding gene in the species Homo sapiens

Histone deacetylase 6 is an enzyme that in humans is encoded by the HDAC6 gene. HDAC6 has emerged as a highly promising candidate to selectively inhibit as a therapeutic strategy to combat several types of cancer and neurodegenerative disorders.

Histone deacetylase 3 is an enzyme encoded by the HDAC3 gene in both humans and mice.

Aspartoacylase is a hydrolytic enzyme (, also called aminoacylase II, ASPA and other names) that in humans is encoded by the ASPA gene. ASPA catalyzes the deacylation of N-acetyl-l-aspartate (N-acetylaspartate) into aspartate and acetate. It is a zinc-dependent hydrolase that promotes the deprotonation of water to use as a nucleophile in a mechanism analogous to many other zinc-dependent hydrolases. It is most commonly found in the brain, where it controls the levels of N-acetyl-l-aspartate. Mutations that result in loss of aspartoacylase activity are associated with Canavan disease, a rare au

Arylformamidase (, AFMID) is an enzyme that catalyzes the chemical reaction

Histone deacetylase 10 is an enzyme that in humans is encoded by the HDAC10 gene. HDAC10 is a class IIb HDAC. It specifically has selectivity for long, slender polyamines like N8-acetylspermidine.

In enzymology, a nicotinamidase () is an enzyme that catalyzes the chemical reaction

In enzymology, a beta-ureidopropionase () is an enzyme that catalyzes the chemical reaction

Amidohydrolases (or amidases) are a type of hydrolase that acts upon amide bonds.

class of enzymes

protein-coding gene in the species Homo sapiens

class of enzymes

class of enzymes

class of enzymes

class of enzymes