ceramidase
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Ceramidase (, acylsphingosine deacylase, glycosphingolipid ceramide deacylase) is an enzyme which cleaves fatty acids from ceramide, producing sphingosine (SPH) which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate (S1P).
In the Vinony graph
Vinony's link graph records 300 inbound references to ceramidase, and connects out to Q180686, Q229883 and activation induced cytidine deaminase.
It is catalogued under the topic EC 3.5.1.
Vinony links it to 7 Wikipedia language editions.
Research
1,287 papers- Neutral ceramidase regulates breast cancer progression by metabolic programming of TREM2-associated macrophages.Nature communications · 2024
- Alkaline ceramidase family: The first two decades.Cellular signalling · 2021
- Targeting acid ceramidase enhances antitumor immune response in colorectal cancer.Journal of advanced research · 2024
- Acid Ceramidase, a Double-edged Sword in Cancer Aggression: A Minireview.Current cancer drug targets · 2021
- Measurement of neutral ceramidase activity in vitro and in vivo.Analytical biochemistry · 2022
via PubMed
Wikidata facts
Show 2 more facts
- EC enzyme number
- 3.5.1.23
- Commons category
- Ceramidase
Sources (1)
via Wikidata · CC0
~2 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- External links
Ceramidase (, acylsphingosine deacylase, glycosphingolipid ceramide deacylase) is an enzyme which cleaves fatty acids from ceramide, producing sphingosine (SPH) which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate (S1P).
== Function ==
Excerpted from Wikipedia’s “ceramidase” article, available under the CC BY-SA 4.0 licence.