Phenyl compounds

4-Phenylthiosemicarbazide (4-PTSC) is a thiosemicarbazide used as an agricultural chemical and pesticide. It also possesses antibacterial properties attributed to electron delocalization in the thiosemicarbazide moiety.

Phenylacetylglutamine is a product formed by the conjugation of phenylacetate and glutamine. It is a common metabolite that occurs naturally in human urine.

Phenglutarimide (brand names Aturbal and Aturbane) is an anticholinergic used as an antiparkinsonian agent.

Fenpiprane is a drug used for the management of functional gastrointestinal disorders.

'''trans-2-Phenyl-1-cyclohexanol''' is an organic compound. The two enantiomers of this compound are used in organic chemistry as chiral auxiliaries.

Centalun was developed by Boehringer Ingelheim in 1962 and is a psycholeptic drug with hypnotic and sedative effects, via allosteric agonism of the GABAA receptor. It was previously used for sedation in medical procedures such as surgery, orthopedics and gynecology, although it is no longer in clinical use. Despite its history of clinical use, centalun was never incorporated into the CSA and therefore remains unregulated as a drug of abuse.

Solasulfone is an antileprotic drug developed from the parent compound sulphetrone. It was first described and evaluated in the 1930s and 1940s as an antibacterial agent for the treatment of tuberculosis and various other infections, and later found to be effective in the treatment of leprosy.

Lanicemine (AZD6765) is a low-trapping NMDA receptor antagonist that was under development by AstraZeneca for the management of severe and treatment-resistant depression. Lanicemine differs from ketamine in that it is a low-trapping NMDA receptor antagonist, showing similar rapid-acting antidepressant effects to ketamine in clinical trials but with little or no psychotomimetic side effects. However, lanicemine did not meet study endpoints, and its development was terminated by AstraZeneca in 2013.

Vesamicol is an experimental drug, acting presynaptically by inhibiting acetylcholine (ACh) uptake into synaptic vesicles and reducing its release. Vesamicol may have applications for the treatment of adenocarcinoma in situ of the lung.

chemical compound

1,2-Diphenyl-1,2-ethylenediamine, DPEN, is an organic compound with the formula H2NCHPhCHPhNH2, where Ph is phenyl (C6H5). DPEN exists as three stereoisomers: meso and two enantiomers S,S- and R,R-. The chiral diastereomers are used in asymmetric hydrogenation. Both diastereomers are bidentate ligands.

β-Nitrostyrene is an aromatic compound and a nitroalkene used in the synthesis of the slimicide .

2,2-Diphenylpropylamine is a form of diphenylpropylamine.

Pulvinone, an organic compound belonging to the esters, lactones, alcohols and butenolides classes, is a yellow crystalline solid. Although the pulvinone is not a natural product, several naturally occurring hydroxylated derivatives are known. These hydroxylated pulvinones are produced by fungal species, such as the in Europe common Larch Bolete (Boletus elegans, also known as Suillus grevillei), or by moulds such as Aspergillus terreus.

Azaprocin is a drug which is an opioid analgesic with approximately ten times the potency of morphine, and a fast onset and short duration of action. It was discovered in 1963, but has never been marketed.

class of chemical compounds

Tetraphenyllead is an organolead compound with the chemical formula or . It is a white solid.

3-Phenylazoacetylacetone (or phenyl-azo-acetylaceton) is a chemical compound used as an intermediate in the preparation of biologically active compounds, chelating agents, and dyes.

Binedaline (also called binodaline or binedaline hydrochloride) is a drug that was investigated as an antidepressant in the 1980s but was never marketed. It acts as a selective norepinephrine reuptake inhibitor (Ki = 25 nM), with relatively insignificant influence on the serotonin (Ki = 847 nM) and dopamine (Ki >= 2 μM) transporters. It has negligible affinity for the α-adrenergic, mACh, H1, or 5-HT2 receptors.

Benzoylacetone is the organic compound with the nominal formula C6H5C(O)CH2C(O)CH3. As a 1,3-dicarbonyl, it is a precursor to many heterocycles, such as pyrazoles. It exists predominantly as the enol tautomer C6H5C(OH)=CHC(O)CH3. Its conjugate base (pKa=8.7) forms stable complexes with transition metals and lanthanides.

Acrylophenone is an organic compound with the formula C9H8O. It is prepared using acetophenone, formaldehyde, and an amine hydrochloride in a Mannich reaction. It can be polymerized to poly(phenylvinyl ketone) via radical or anionic mechanisms. It is sometimes used as a comonomer in the manufacturing of certain resins.

RTI-126 ('RTI-4229-126 or (–)-2β-(1,2,4-oxadiazol-5-methyl)-3β-phenyltropane') is a phenyltropane derivative which acts as a potent monoamine reuptake inhibitor and stimulant drug, and has been sold as a designer drug. It is around 5 times more potent than cocaine at inhibiting monoamine reuptake in vitro, but is relatively unselective. It binds to all three monoamine transporters, although still with some selectivity for the dopamine transporter. RTI-126 has a fast onset of effects and short duration of action, and its pharmacological profile in animals is among the closest to cocaine itself

DIOP (2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane) is an organophosphorus compound that is used as a chiral ligand in asymmetric catalysis. It is a white solid that is soluble in organic solvents.

'(R)-2-Methyl-CBS-oxazaborolidine' is an organoboron catalyst that is used in organic synthesis. This catalyst, developed by Shinichi Itsuno and Elias James Corey, is generated by heating (R)-(+)-2-(diphenylhydroxymethyl) pyrrolidine along with trimethylboroxine or methylboronic acid. It is an excellent tool for the synthesis of alcohols in high enantiomeric ratio. Generally, 2-10 mol% of this catalyst is used along with borane-tetrahydrofuran (THF), borane-dimethylsulfide, borane-N,N-diethylaniline, or diborane as the borane source. Enantioselective reduction using chiral oxazaborolidine cata

Fluorolintane (also known as 2-FPPP and 2-F-DPPy) is a dissociative anesthetic drug that has been sold online as a designer drug.

Lophine is the organic compound with the formula . It is a derivative of imidazole wherein all three carbon atoms have phenyl groups as substituents. A white solid, this compound gave the first example of chemiluminescence when its basic solutions were exposed to air. Its chemiluminescence continues to attract attention.

chemical compound

Tetraphenyltin is an organotin compound with the chemical formula , often abbreviated as , where Ph is phenyl. It is a white crystalline solid.

chemical compound

4-Nitrobiphenyl is an organic compound with the formula . It is one of three isomers of nitrobiphenyl and probably the most widely used. It is a precursor to the antioxidant 4-aminobiphenyl. 4-Nitrobiphenyl is readily prepared by nitration of biphenyl. It can also be prepared by cross-coupling reactions.

Alimadol (INN; A-4020) is an opioid analgesic related to methadone which was never marketed.

'(E)-Cinnamonitrile' is an organic compound approved for use as a fragrance in products such as air fresheners. It has a spicy cinnamon/cassia aroma.

Methoxphenidine (methoxydiphenidine, 2-MeO-Diphenidine, MXP) is a dissociative of the diarylethylamine class that has been sold online as a designer drug. Methoxphenidine was first reported in a 1989 patent where it was tested as a treatment for neurotoxic injury. Shortly after the 2013 UK ban on arylcyclohexylamines methoxphenidine and the related compound diphenidine became available on the gray market, where it has been encountered as a powder and in tablet form. Though diphenidine possesses higher affinity for the NMDA receptor, anecdotal reports suggest methoxphenidine has greater oral po