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methoxphenidine
Sign in to saveMethoxphenidine (methoxydiphenidine, 2-MeO-Diphenidine, MXP) is a dissociative of the diarylethylamine class that has been sold online as a designer drug. Methoxphenidine was first reported in a 1989 patent where it was tested as a treatment for neurotoxic injury. Shortly after the 2013 UK ban on arylcyclohexylamines methoxphenidine and the related compound diphenidine became available on the gray market, where it has been encountered as a powder and in tablet form. Though diphenidine possesses higher affinity for the NMDA receptor, anecdotal reports suggest methoxphenidine has greater oral po
Chemical data
- Formula
- C20H25NO
- Molecular weight
- 295.4 g/mol
- IUPAC name
- 1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine
- SMILES
- COC1=CC=CC=C1C(CC2=CC=CC=C2)N3CCCCC3
- InChIKey
- QXXCUXIRBHSITD-UHFFFAOYSA-N
- XLogP
- 4.6
- Polar surface area
- 12.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 295.194
Show 3 more facts
- chemical formula
- C₂₀H₂₅NO
- canonical SMILES
- COC1=CC=CC=C1C(CC2=CC=CC=C2)N3CCCCC3
- Commons category
- Methoxphenidine
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
4 sectionsContents
- Side effects
- Legal status
- See also
- References
Methoxphenidine (methoxydiphenidine, 2-MeO-Diphenidine, MXP) is a dissociative of the diarylethylamine class that has been sold online as a designer drug. Methoxphenidine was first reported in a 1989 patent where it was tested as a treatment for neurotoxic injury. Shortly after the 2013 UK ban on arylcyclohexylamines methoxphenidine and the related compound diphenidine became available on the gray market, where it has been encountered as a powder and in tablet form. Though diphenidine possesses higher affinity for the NMDA receptor, anecdotal reports suggest methoxphenidine has greater oral potency. Of the three isomeric anisyl-substituents methoxphenidine has affinity for the NMDA receptor that is higher than 4-MeO-diphenidine but lower than 3-MeO-diphenidine, a structure–activity relationship shared by the arylcyclohexylamines.
== Side effects ==
Excerpted from Wikipedia’s “methoxphenidine” article, available under the CC BY-SA 4.0 licence.