English
Structure via PubChem · Public domain (PubChem)
phenglutarimide
Sign in to saveAlso known as 3-(2-diethylaminoethyl)-4-phenylpiperidine-2,6-dione
Phenglutarimide (brand names Aturbal and Aturbane) is an anticholinergic used as an antiparkinsonian agent.
Chemical data
- Formula
- C17H24N2O2
- Molecular weight
- 288.4 g/mol
- IUPAC name
- 3-[2-(diethylamino)ethyl]-3-phenylpiperidine-2,6-dione
- SMILES
- CCN(CC)CCC1(CCC(=O)NC1=O)C2=CC=CC=C2
- InChIKey
- BFMBKRQFMIILCH-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 49.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Parkinson disease
via ChEMBL · EBI
Research
14 papers- Stereoselective recognition of the enantiomers of phenglutarimide and of six related compounds by four muscarinic receptor subtypes.British journal of pharmacology · 1996
- [Phenglutarimide in the medical treatment of parkinsonism].La Semana medica · 1960
- The fate of phenglutarimide hydrochloride in the rat and man.Xenobiotica; the fate of foreign compounds in biological systems · 1973
- Stereoselectivity at muscarinic receptor subtypes: observations with the enantiomers of phenglutarimide.Chirality · 1989
- [Aturban (phenglutarimide), a new therapeutic drug for parkinsonism; comparative investigation on the therapy of parkinsonism].Schweizerische medizinische Wochenschrift · 1958
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 288.184
Show 3 more facts
- chemical formula
- C₁₇H₂₄N₂O₂
- canonical SMILES
- CCN(CC)CCC1(CCC(=O)NC1=O)C2=CC=CC=C2
- subject has role
- anticholinergic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Phenglutarimide (brand names Aturbal and Aturbane) is an anticholinergic used as an antiparkinsonian agent.
== References ==
Excerpted from Wikipedia’s “phenglutarimide” article, available under the CC BY-SA 4.0 licence.