1,3-diphenylurea

Also known as N,N'-diphenylurea, carbanilide, sym-diphenylurea, 1,3-diphenylcarbamide, s-diphenylurea, N-phenyl-N'-phenylurea, diphenylurea, diphenylcarbamide

1,3-Diphenylurea is a phenylurea-type compound with the formula (PhNH)2CO (Ph = C6H5). It is a colorless solid that is prepared by transamidation of urea with aniline.

Research

38 papers

Characterization, Preparation, and Promotion of Plant Growth of 1,3-Diphenylurea/β-Cyclodextrin Derivatives Inclusion Complexes.ACS omega · 2023
Discovery of new 1,3-diphenylurea appended aryl pyridine derivatives as apoptosis inducers through c-MET and VEGFR-2 inhibition: design, synthesis, in vivo and in silico studies.RSC medicinal chemistry · 2024
Dual-target-directed 1,3-diphenylurea derivatives: BACE 1 inhibitor and metal chelator against Alzheimer's disease.Bioorganic & medicinal chemistry · 2010
Disruption of c-Myc/Max heterodimerization induced by a novel anticancer agent endowed with 1,3-diphenylurea moiety: an in silico, chemoproteomics-based, and in vitro combined approach.International journal of biological macromolecules · 2025
Synthesis, in vitro, and in silico study of novel pyridine based 1,3-diphenylurea derivatives as tyrosinase inhibitors.Bioorganic chemistry · 2024

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1,3-Diphenylurea is a phenylurea-type compound with the formula (PhNH)2CO (Ph = C6H5). It is a colorless solid that is prepared by transamidation of urea with aniline.

DPU is a cytokinin, a type of plant hormone that induces flower development. The cytokinin effect of DPU is relatively low, but other more potent phenylurea-type cytokinins have been reported.