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1,3-thiazole

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1,3-thiazole

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Also known as FEMA 3615, 5H-1,3-Thiazole, LOM, thiazole

Thiazole (), or 1,3-thiazole, is a 5-membered heterocyclic compound that contains both sulfur and nitrogen. The term 'thiazole' also refers to a large family of derivatives. Thiazole itself is a pale yellow liquid with a pyridine-like odor and the molecular formula C3H3NS. The thiazole ring is notable as a component of the vitamin thiamine (B1).

Chemical data

Formula
C3H3NS
Molecular weight
85.13 g/mol
IUPAC name
1,3-thiazole
SMILES
C1=CSC=N1
InChIKey
FZWLAAWBMGSTSO-UHFFFAOYSA-N
XLogP
0.4
Polar surface area
41.1 Ų
H-bond donors
0
H-bond acceptors
2
Formal charge
0

via PubChem

Wikidata facts

Has part
carbon
Mass
84.999
Show 5 more facts
canonical SMILES
C1=CSC=N1
chemical formula
C₃H₃NS
Commons category
Thiazole
melting point
-33.0
Sources (3)

via Wikidata · CC0

~6 min read

Encyclopedic overview

7 sections
Contents
  • Molecular and electronic structure
  • Occurrence of thiazoles and thiazolium salts
  • Synthesis
  • Biosynthesis
  • Reactions
  • Thiazolium salts
  • References

Thiazole (), or 1,3-thiazole, is a 5-membered heterocyclic compound that contains both sulfur and nitrogen. The term 'thiazole' also refers to a large family of derivatives. Thiazole itself is a pale yellow liquid with a pyridine-like odor and the molecular formula C3H3NS. The thiazole ring is notable as a component of the vitamin thiamine (B1).

==Molecular and electronic structure== Thiazoles are members of the azoles, heterocycles that include imidazoles and oxazoles. Thiazole can also be considered a functional group when part of a larger molecule.

Excerpted from Wikipedia’s “1,3-thiazole” article, available under the CC BY-SA 4.0 licence.

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