ciclopirox

Key facts

Drug.verifiedrevid

460036027

Drug.image

Ciclopirox.svg

Drug.image_class

skin-invert-image

Drug.width

180

Drug.caption

Above: molecular structure of ciclopirox Below: 3D representation of a ciclopirox molecule

Drug.image2

Ciclopirox 3D.png

Drug.image_class2

bg-transparent

Drug.tradename

Penlac Nail Lacquer, others

Drug.MedlinePlus

a604021

Drug.DailyMedID

Ciclopirox

Drug.routes_of_administration

Topical

Drug.ATC_prefix

D01

Drug.ATC_suffix

AE14

Drug.legal_AU

S2

Drug.legal_CA

Rx-only

Drug.legal_US

Rx-only

Drug.bioavailability

<5% with prolonged use

Drug.protein_bound

94 to 97%

via Wikipedia infobox

Chemical data

Formula

C12H17NO2

Molecular weight

207.27 g/mol

IUPAC name

6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one

SMILES

CC1=CC(=O)N(C(=C1)C2CCCCC2)O

InChIKey

SCKYRAXSEDYPSA-UHFFFAOYSA-N

XLogP

2

Polar surface area

40.5 Ų

H-bond donors

1

H-bond acceptors

2

Formal charge

0

via PubChem

• Ciclopirox.2006
• Ciclopirox: an overview.International journal of dermatology · 2001
• Ciclopirox Hydroxypropyl Chitosan (HPCH) Nail Lacquer: A Review of Its Use in Onychomycosis.Dermatology and therapy · 2020
• Reposition of the Fungicide Ciclopirox for Cancer Treatment.Recent patents on anti-cancer drug discovery · 2021
• Onychomycosis: Treatment and prevention of recurrence.Journal of the American Academy of Dermatology · 2019

via PubMed