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nizatidine
Sign in to saveAlso known as Axid®, LY-139037, Tazac
Nizatidine is a histamine H2 receptor antagonist that inhibits stomach acid production, and is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
Chemical data
- Formula
- C12H21N5O2S2
- Molecular weight
- 331.5 g/mol
- IUPAC name
- 1-N'-[2-[[2-[(dimethylamino)methyl]-1,3-thiazol-4-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine
- SMILES
- CNC(=C[N+](=O)[O-])NCCSCC1=CSC(=N1)CN(C)C
- InChIKey
- SGXXNSQHWDMGGP-UHFFFAOYSA-N
- XLogP
- 1.6
- Polar surface area
- 140 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
~2 min read
Encyclopedic overview
6 sectionsContents
- Medical use
- Adverse effects
- History and development
- Society and culture
- Brand names
- References
Nizatidine is a histamine H2 receptor antagonist that inhibits stomach acid production, and is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
It was patented in 1980 and approved for medical use in 1988. It was developed by Eli Lilly.
Excerpted from Wikipedia’s “nizatidine” article, available under the CC BY-SA 4.0 licence.