omoconazole

Chemical data

Formula

C20H17Cl3N2O2

Molecular weight

423.7 g/mol

IUPAC name

1-[(Z)-1-[2-(4-chlorophenoxy)ethoxy]-1-(2,4-dichlorophenyl)prop-1-en-2-yl]imidazole

SMILES

C/C(=C(\C1=C(C=C(C=C1)Cl)Cl)/OCCOC2=CC=C(C=C2)Cl)/N3C=CN=C3

InChIKey

JMFOSJNGKJCTMJ-ZHZULCJRSA-N

XLogP

5.8

Polar surface area

36.3 Ų

H-bond donors

0

H-bond acceptors

3

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

via ChEMBL · EBI

• Therapeutic effects of omoconazole nitrate on experimental tinea pedis, an intractable dermatophytosis, in guinea-pigs.The Journal of antimicrobial chemotherapy · 1997
• Study of the effective dose of a topical antifungal agent, omoconazole nitrate, on the basis of percutaneous pharmacokinetics in guinea-pigs and mice.The Journal of pharmacy and pharmacology · 1997
• [In vitro antifungal activity of omoconazole nitrate, a new imidazole antimycotic].The Japanese journal of antibiotics · 1993
• Structure-activity relationships of 2-(1H-imidazol-1-yl)vinyl ethers. Route to the new broad-spectrum antifungal agent omoconazole.Annals of the New York Academy of Sciences · 1988
• Overview of medically important antifungal azole derivatives.Clinical microbiology reviews · 1988

via PubMed

Wikidata facts

Mass

422.036

via Wikidata · CC0