3-methoxymorphinan
Sign in to save3-Methoxymorphinan is an inactive metabolite of both dextromethorphan and levomethorphan, and has been shown to produce local anesthetic effects. It is the CYP3A4 metabolite of the aforementioned drugs, and is itself metabolized by the liver enzyme CYP2D6.
Wikidata facts
- Mass
- 257.178
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- chemical formula
- C₁₇H₂₃NO
- canonical SMILES
- COC1=CC2=C(CC3C4C2(CCCC4)CCN3)C=C1
- isomeric SMILES
- COC1=CC2=C(C[C@@H]3[C@H]4[C@@]2(CCCC4)CCN3)C=C1
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3-Methoxymorphinan is an inactive metabolite of both dextromethorphan and levomethorphan, and has been shown to produce local anesthetic effects. It is the CYP3A4 metabolite of the aforementioned drugs, and is itself metabolized by the liver enzyme CYP2D6.
== See also == 3-hydroxymorphinan Dextrorphan Dextromethorphan Levomethorphan Morphinan
Connections
medication
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nervous system
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digital object identifier
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chemical formula
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molar mass
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Q180686
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CAS Registry Number
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PubChem
Entity
dextromethorphan
Entity
Q2311683
Entity
Q22908627
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International Chemical Identifier
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European Chemicals Agency
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Unique Ingredient Identifier
Entity
cytochrome P450 family 3 subfamily A member 4
Protein
cytochrome P450 family 2 subfamily D member 6
Protein
regulation of therapeutic goods
Entity
(-)-morphinan
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dextrorphan
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levomethorphan
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