Skip to content
methoxyphedrine
EntityQ2506962· pop 10· linked from 1,501 articles

methoxyphedrine

Sign in to save

Methedrone ('''para-methoxymethcathinone, 4-methoxymethcathinone, bk-PMMA, PMMC, methoxyphedrine, 4-MeOMC') is a recreational drug of the cathinone chemical class. Chemically, methedrone is closely related to para''-methoxymethamphetamine (PMMA), methylone and mephedrone. Methedrone received media attention in 2009 after the death of two young Swedish men. In both cases toxicology analysis showed methedrone was the only drug present in both men during the time of their overdose and subsequent deaths.

Wikidata facts

Has part
carbon
Mass
193.11
Show 4 more facts
canonical SMILES
CC(C(=O)C1=CC=C(C=C1)OC)NC
chemical formula
C₁₁H₁₅NO₂
Commons category
Methedrone
different from
mephedrone
Sources (3)

via Wikidata · CC0

~12 min read

Encyclopedic overview

21 sections
Contents
  • Uses
  • Dosage
  • Adverse effects
  • Overdose
  • Acute toxicity
  • Chronic toxicity
  • Pharmacology
  • Mechanism of action
  • Pharmacokinetics
  • Chemistry
  • Structure
  • Synthesis
  • Reactivity
  • History
  • Society and culture
  • Names
  • Recreational use
  • Legal status
  • Other animals
  • Mice
  • References

Methedrone ('''para-methoxymethcathinone, 4-methoxymethcathinone, bk-PMMA, PMMC, methoxyphedrine, 4-MeOMC') is a recreational drug of the cathinone chemical class. Chemically, methedrone is closely related to para-methoxymethamphetamine (PMMA), methylone and mephedrone. Methedrone received media attention in 2009 after the death of two young Swedish men. In both cases toxicology analysis showed methedrone was the only drug present in both men during the time of their overdose and subsequent deaths.

==Uses== ===Dosage=== There is little information available about how Methedrone is dosed. According to users, a single dose of Methedrone varies from 50 to 500 mg with effects lasting 45 minutes to two hours. There are at least two cases known of fatal intoxications with Methedrone. In the first case, the postmortem femoral blood sample of the patient contained a concentration of 8.4 μg/g Methedrone, the patient died 16 hours after consumption (with polysubstance use detected). In the second body the concentration in the femoral blood sample was 9.6 μg/g, with Methedrone being the only toxic compound detected. The scientific investigation of these cases suggests that the Methedrone alone was responsible for these deaths and that the concentrations in the femoral blood represent the fatal levels of methedrone. These studies show that the therapeutic index (or safety ratio) is low compared to other illegal drugs like Amphetamine. A fatal dose is likely to be around 8 μg/g whereas the dose among users varies from 0.1 to 4.8 μg/g blood according to studies.

Excerpted from Wikipedia’s “methoxyphedrine” article, available under the CC BY-SA 4.0 licence.