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4',7-dihydroxyflavone

Structure via PubChem · Public domain (PubChem)

EntityQ15410218· pop 5· linked from 751 articles

4',7-dihydroxyflavone

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4′,7-Dihydroxyflavone is a flavone. It is found in Medicago truncatula in relation with the root nodulation symbiont Sinorhizobium meliloti or in seeds of Sophora viciifolia.

In the Vinony graph

Within Vinony's link graph, 4',7-dihydroxyflavone is referenced by 751 other articles, and connects out to (+)-catechin, butorphanol and opium.

It is catalogued under topics including Chembox image size set, Flavones and Kappa-opioid receptor antagonists.

Its subject is documented across 4 Wikipedia language editions.

Chemical data

Formula
C15H10O4
Molecular weight
254.24 g/mol
IUPAC name
7-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
SMILES
C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C=C3)O)O
InChIKey
LCAWNFIFMLXZPQ-UHFFFAOYSA-N
XLogP
3.3
Polar surface area
66.8 Ų
H-bond donors
2
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of
flavone
Mass
254.057909
Show 5 more facts
found in taxon
Sophora davidii
canonical SMILES
C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C=C3)O)O
chemical formula
C₁₅H₁₀O₄
has characteristic
bitterness
Commons category
4',7-Dihydroxyflavone
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

2 sections
Contents
  • See also
  • References

4′,7-Dihydroxyflavone is a flavone. It is found in Medicago truncatula in relation with the root nodulation symbiont Sinorhizobium meliloti or in seeds of Sophora viciifolia.

Like many other flavonoids, 4′,7-dihydroxyflavone has been found to possess activity at opioid receptors in vitro. Specifically, it acts as an antagonist of the μ-opioid receptor and, with lower affinity, of the κ- and δ-opioid receptors.

Excerpted from Wikipedia’s “4',7-dihydroxyflavone” article, available under the CC BY-SA 4.0 licence.

Available in 4 languages

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