7,12-Dimethylbenz[a]anthracen

Also known as 1,4-Dimethyl-2,3-benzphenanthrene, 9,10-Dimethylbenz(a)anthracene, 7,12-Dimethylbenzanthrancene, 7,12-Dimethylbenzanthracene, 7,12-Dimethyl-1:2-benz(a)anthracene, 7,12-Dimethyl-1,2-benzanthracene, 7,12-DMBA, 6,7-Dimethyl-1,2-benzanthracene

Research

6,388 papers

Kolaviron Ameliorates 7, 12-Dimethylbenzanthracene - Induced Mammary Damage.Anti-cancer agents in medicinal chemistry · 2022
Constitutive expression of cytochrome P450 1B1 endows testicular Leydig cells with susceptibility to 7,12-dimethylbenzanthracene-induced cell death.The Journal of toxicological sciences · 2022
Maternal dietary zinc status alters offspring female mammary gland development and response to acute 7,12-dimethylbenzanthracene insult.Biotechnic & histochemistry : official publication of the Biological Stain Commission · 2023
Chemically induced carcinogenesis: a comparison of 1-methyl-1-nitrosourea, 7,12-dimethylbenzanthracene,diethylnitroso-amine and azoxymethan models (minireview).Endocrine regulations · 2001
Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin.Cancer letters · 1994

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Wikidata facts

Article · Deutsch

7,12-Dimethylbenzo[a]anthracen, meist mit DMBA abgekürzt, ist ein polycyclischer aromatischer Kohlenwasserstoff (PAK). Der Grundkörper der Verbindung ist Benzo[a]anthracen. DMBA ist stark krebserregend, eines der potentesten Karzinogene und einer der stärksten krebserregenden polycyclischen aromatischen Kohlenwasserstoffe. Es wird in der Onkologie zum Auslösen von Tumoren in Modellorganismen verwendet.

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