aicar
Sign in to saveAlso known as 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, Aica ribonucleotide, AICA-ribonucleotide, acadesine 5'-monophosphate, {[(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid, 5'-Phosphoribosyl-5-amino-4-imidazole carboxamide, Aminoimidazole carboxamide ribonucleotide, 5'-P-Ribosyl-5-amino-4-imidazole carboxamide
chemical compound
Research
2,697 papers- AICAR confers prophylactic cardioprotection in doxorubicin-induced heart failure in rats.Journal of molecular and cellular cardiology · 2024
- AICAr, a Widely Used AMPK Activator with Important AMPK-Independent Effects: A Systematic Review.Cells · 2021
- Liposome-encapsulated AICAR hydrogel regulates macrophage metabolic reprogramming via SIK1 activation to alleviate osteoarthritis.Journal of nanobiotechnology · 2025
- Administration of AICAR, an AMPK Activator, Prevents and Reverses Diabetic Polyneuropathy (DPN) by Regulating Mitophagy.International journal of molecular sciences · 2024
- AICAR attenuates ischemia-reperfusion-induced AKI by modulating AMPK-TXNIP-NLRP3 pathway and energy metabolism.Cellular and molecular life sciences : CMLS · 2026
via PubMed
Wikidata facts
- Mass
- 338.063
Show 6 more facts
- chemical formula
- C₉H₁₅N₄O₈P
- found in taxon
- Arabidopsis thaliana
- canonical SMILES
- C1=NC(=C(N1C2C(C(C(O2)COP(=O)(O)O)O)O)N)C(=O)N
- isomeric SMILES
- C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)N)C(=O)N
- subject has role
- primary metabolite
- Commons category
- 5-Aminoimidazole-4-carboxamide ribonucleotide
via Wikidata · CC0