EntityQ408529· pop 36· linked from 251 articles

amikacin

Amikacin is an antibiotic medication used for a number of bacterial infections. This includes joint infections, intra-abdominal infections, meningitis, pneumonia, sepsis, and urinary tract infections. It is also used for the treatment of multidrug-resistant tuberculosis. It is used by injection into a vein using an IV or into a muscle.

Key facts

Drug.Watchedfields: changed
Drug.verifiedrevid: 464364466
Drug.image: Amikacin.svg
Drug.image_class: skin-invert-image
Drug.image2: Amikacin 3D ball-and-stick 4P20.png
Drug.image_class2: bg-transparent
Drug.tradename: Amikin, Amiglyde-V, Arikayce, others
Drug.MedlinePlus: a682661
Drug.DailyMedID: Amikacin
Drug.pregnancy_AU: D
Drug.routes_of_administration: Intramuscular, intravenous, inhalation
Drug.class: Aminoglycoside
Drug.ATC_prefix: D06
Drug.ATC_suffix: AX12
Drug.ATC_supplemental: , , , , , ,
Drug.legal_AU: S4
Drug.legal_UK: POM
Drug.legal_US: Rx-only

via Wikipedia infobox

Research

14,079 papers

Amikacin.Annals of internal medicine · 1981
Amikacin.Tuberculosis (Edinburgh, Scotland) · 2008
Amikacin.Lancet (London, England) · 1977
An overview of amikacin.Therapeutic drug monitoring · 1985
Amikacin. A new aminoglycoside antibiotic.Minnesota medicine · 1978

via PubMed

Article

13 sections

Contents

Medical uses
Available forms
Special populations
Adverse effects
Contraindications
Interactions
Pharmacology
Mechanism of action
Resistance
Pharmacokinetics
Chemistry
Veterinary uses
References

Amikacin, like other aminoglycoside antibiotics, can cause hearing loss, balance problems, and kidney problems. Other side effects include paralysis, resulting in the inability to breathe. If used during pregnancy it may cause permanent deafness in the baby. Amikacin works by blocking the function of the bacteria's 30S ribosomal subunit, making it unable to produce proteins.