phenobarbital
Sign in to savePhenobarbital, also known as phenobarbitone, sold under the brand name Luminal among others, is a medication of the barbiturate type. It is recommended by the World Health Organization (WHO) for the treatment of certain types of epilepsy in developing countries. In the developed world, it is commonly used to treat seizures in young children, while other medications are generally used in older children and adults. It is also used for veterinary purposes.
Key facts
- Drug.verifiedrevid
- 464200457
- Drug.image
- Phenobarbital2DACS.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 120
- Drug.alt
- 2D chemical structure of phenobarbital
- Drug.image2
- Phenobarbital 3D xtal ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 140
- Drug.alt2
- 3D ball-and-stick model of phenobarbital
- Drug.tradename
- Luminal, Sezaby, others
- Drug.MedlinePlus
- a682007
- Drug.DailyMedID
- Phenobarbital
- Drug.pregnancy_AU
- D
- Drug.dependency_liability
- High
- Drug.routes_of_administration
- By mouth, rectal, parenteral
- Drug.class
- Barbiturate
- Drug.ATC_prefix
- N03
- Drug.ATC_suffix
- AA02
via Wikipedia infobox
Article
15 sectionsContents
- Medical uses
- Other uses
- Side effects
- Contraindications
- Overdose
- Mechanism of action
- Pharmacokinetics
- History
- Society and culture
- Names
- Synthesis
- Regulation
- Selected overdoses
- Veterinary uses
- References
Phenobarbital, also known as phenobarbitone, sold under the brand name Luminal among others, is a medication of the barbiturate type. It is recommended by the World Health Organization (WHO) for the treatment of certain types of epilepsy in developing countries. In the developed world, it is commonly used to treat seizures in young children, while other medications are generally used in older children and adults. It is also used for veterinary purposes.
It may be administered by slow intravenous infusion (IV infusion), intramuscularly (IM), or orally (swallowed by mouth). Subcutaneous administration is not recommended. The IV or IM (injectable forms) may be used to treat status epilepticus if other drugs fail to achieve satisfactory results. Phenobarbital is occasionally used to treat insomnia, anxiety, and benzodiazepine withdrawal (as well as withdrawal from certain other drugs in specific circumstances), and prior to surgery as an anxiolytic and to induce sedation. It usually begins working within five minutes when used intravenously and half an hour when administered orally. Its effects last for between four hours and two days.