pregnanediol
Sign in to saveAlso known as 5β-pregnane-3α,20α-diol, pregnandiol
Pregnanediol, or 5β-pregnane-3α,20α-diol, is an inactive metabolic product of progesterone. A test can be done to measure the amount of pregnanediol in urine, which offers an indirect way to measure progesterone levels in the body.
In the Vinony graph
Within Vinony's link graph, pregnanediol is referenced by 329 other articles, and connects out to androstenedione, androstenediol and androstenol.
It sits within the topics 5β-Pregnanes, ECHA InfoCard ID from Wikidata and Human metabolites.
Its subject is documented across 7 Wikipedia language editions.
Research
3,347 papers- [Pregnanediol (P2)].Nihon rinsho. Japanese journal of clinical medicine · 1995
- Progesterone and pregnanediol.Contributions to gynecology and obstetrics · 1976
- [Pregnanediol (P2), pregnanetriol (P3)].Nihon rinsho. Japanese journal of clinical medicine · 2005
- [Pregnanediol (P2), pregnanetriol (P3)].Nihon rinsho. Japanese journal of clinical medicine · 1999
- Progesterone and pregnanediol.Fertility and sterility · 1959
via PubMed
Wikidata facts
- Mass
- 320.27153
Show 4 more facts
- Commons category
- Pregnanediol
- chemical formula
- C₂₁H₃₆O₂
- canonical SMILES
- CC(C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C)O
- isomeric SMILES
- C1C[C@@H](O)C[C@@]2([H])CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)O)[C@@]4(C)CC[C@]3([H])[C@@]12C
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Chemistry
- See also
- References
Pregnanediol, or 5β-pregnane-3α,20α-diol, is an inactive metabolic product of progesterone. A test can be done to measure the amount of pregnanediol in urine, which offers an indirect way to measure progesterone levels in the body.
From the urine of pregnant women from London clinics, Guy Frederic Marrian isolated a substance that contained two hydroxyl groups and could be converted into a diacetate with acetic anhydride. However, the formula had not been clearly clarified. Almost at the same time, Adolf Butenandt at the Chemical University Laboratory in Göttingen investigated the constituents of pregnant urine and clarified the structure of the diol. The name pregnandiol, coined by Butenandt, is derived from the Latin verb praegnans (pregnant) or the English pregnant and pregnancy. This gave rise to the name pregnane for the underlying parent hydrocarbon.
Excerpted from Wikipedia’s “pregnanediol” article, available under the CC BY-SA 4.0 licence.