AQP1
Sign in to saveAlso known as AQP-CHIP, CHIP28, CO, aquaporin 1 (Colton blood group)
Aquaporin 1 (AQP-1) is a protein that in humans is encoded by the AQP1 gene.
Gene data
AQP1- Name
- aquaporin 1 (Colton blood group)
- Type
- protein-coding
- Position
- 30,910,755–30,925,517 (+)
- Aliases
- AQP-CHIP, CHIP28, CO
- Ensembl
- ENSG00000240583
- RefSeq RNA
- NM_000385.3, NM_001185060.1, NM_001185061.1, NM_001185062.1, NM_001329872.2
- RefSeq protein
- NP_001316801.1, NP_932766.1
This gene encodes a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imbalance in ocular fluid movement. [provided by RefSeq, Aug 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
aquaporin 1 (Colton blood group)
- Symbol
- AQP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:30,910,755-30,925,517
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~2 min read
Encyclopedic overview
5 sectionsContents
- Function
- See also
- References
- Further reading
- External links
Aquaporin 1 (AQP-1) is a protein that in humans is encoded by the AQP1 gene.
AQP-1 is a widely expressed water channel, whose physiological function has been most thoroughly characterized in the kidney. It is found in the basolateral and apical plasma membranes of the proximal tubules, the descending limb of the loop of Henle, and in the descending portion of the vasa recta. Additionally, it is found in red blood cells, vascular endothelium, the gastrointestinal tract, sweat glands, lungs, and the central nervous system.
Excerpted from Wikipedia’s “AQP1” article, available under the CC BY-SA 4.0 licence.