GJD4
Sign in to saveAlso known as CX40.1, gap junction protein delta 4
Gap junction delta-4 protein (GJD4), also known as connexin-40.1 (Cx40.1), is a protein that in humans is encoded by the GJD4 gene.
Gene data
GJD4- Name
- gap junction protein delta 4
- Type
- protein-coding
- Position
- 35,605,341–35,608,935 (+)
- Aliases
- CX40.1
- Ensembl
- ENSG00000177291
- RefSeq RNA
- NM_153368.3
- RefSeq protein
- NP_699199.2
Connexins, such as GJD4, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
gap junction protein delta 4
- Symbol
- GJD4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:35,605,341-35,608,935
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 17692
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/219770
- genomic end
- 35897863
- genomic start
- 35605341
- chromosome
- human chromosome 10
- cytogenetic location
- 10p11.21
- expressed in
- muscle
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Function
- References
Gap junction delta-4 protein (GJD4), also known as connexin-40.1 (Cx40.1), is a protein that in humans is encoded by the GJD4 gene.
== Function == Connexins, such as GJD4, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.
Excerpted from Wikipedia’s “GJD4” article, available under the CC BY-SA 4.0 licence.