Structure via PubChem · Public domain (PubChem)
آرتمتر
Sign in to saveAlso known as Artemetheri, beta-Artemether, (1R,4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane, Dihydroqinghaosu methyl ether, Artemisininelactol methyl ether, Methyl-dihydroartemisinine, Artemetero, SM-224
Artemether is a medication used for the treatment of malaria. The injectable form is specifically used for severe malaria rather than quinine. In adults, it may not be as effective as artesunate. It is given by injection in a muscle. It is also available by mouth in combination with lumefantrine, known as artemether/lumefantrine.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 457818137
- Drug.IUPAC_name
- (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]-2-benzopyran
- Drug.image
- artemether.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 150
- Drug.image2
- Artemether ball-and-stick model from xtal 2007.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 200
- Drug.tradename
- Many
- Drug.pregnancy_US
- C
- Drug.legal_UK
- POM
- Drug.legal_status
- Rx only
- Drug.routes_of_administration
- Intramuscular Oral
- Drug.CAS_number
- 71963-77-4
- Drug.ATC_prefix
- P01
- Drug.ATC_suffix
- BE02
via Wikipedia infobox
Chemical data
- Formula
- C16H26O5
- Molecular weight
- 298.37 g/mol
- IUPAC name
- (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
- SMILES
- C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC)C
- InChIKey
- SXYIRMFQILZOAM-HVNFFKDJSA-N
- XLogP
- 3.1
- Polar surface area
- 46.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2009
- Admin. routes
- oral
- Indications
- neoplasm, malaria, Plasmodium falciparum malaria, HIV infection
via ChEMBL · EBI
Research
2,914 papers- Artemether for severe malaria.The Cochrane database of systematic reviews · 2019
- Artemether for severe malaria.The Cochrane database of systematic reviews · 2014
- Artemether-lumefantrine for uncomplicated malaria: a systematic review.Tropical medicine & international health : TM & IH · 2004
- Artemether ameliorates DSS-induced ulcerative colitis by modulating macrophage polarization.International immunopharmacology · 2025
- Artemether ameliorates adriamycin induced cardiac atrophy in mice.Molecular medicine reports · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 298.178
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₆H₂₆O₅
- isomeric SMILES
- C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC)C
- canonical SMILES
- CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C
- World Health Organisation international non-proprietary name
- artemether
via Wikidata · CC0