Structure via PubChem · Public domain (PubChem)
Artemeter
Sign in to saveAlso known as Artemetheri, beta-Artemether, (1R,4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane, Dihydroqinghaosu methyl ether, Artemisininelactol methyl ether, Methyl-dihydroartemisinine, Artemetero, SM-224
kimyasal bileşik
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 457818137
- Drug.IUPAC_name
- (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]-2-benzopyran
- Drug.image
- artemether.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 150
- Drug.image2
- Artemether ball-and-stick model from xtal 2007.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 200
- Drug.tradename
- Many
- Drug.pregnancy_US
- C
- Drug.legal_UK
- POM
- Drug.legal_status
- Rx only
- Drug.routes_of_administration
- Intramuscular Oral
- Drug.CAS_number
- 71963-77-4
- Drug.ATC_prefix
- P01
- Drug.ATC_suffix
- BE02
via Wikipedia infobox
Chemical data
- Formula
- C16H26O5
- Molecular weight
- 298.37 g/mol
- IUPAC name
- (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
- SMILES
- C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC)C
- InChIKey
- SXYIRMFQILZOAM-HVNFFKDJSA-N
- XLogP
- 3.1
- Polar surface area
- 46.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2009
- Admin. routes
- oral
- Indications
- neoplasm, malaria, Plasmodium falciparum malaria, HIV infection
via ChEMBL · EBI
Research
2,914 papers- Artemether for severe malaria.The Cochrane database of systematic reviews · 2019
- Artemether for severe malaria.The Cochrane database of systematic reviews · 2014
- Artemether-lumefantrine for uncomplicated malaria: a systematic review.Tropical medicine & international health : TM & IH · 2004
- Artemether ameliorates DSS-induced ulcerative colitis by modulating macrophage polarization.International immunopharmacology · 2025
- Artemether ameliorates adriamycin induced cardiac atrophy in mice.Molecular medicine reports · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 298.178
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₆H₂₆O₅
- isomeric SMILES
- C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC)C
- canonical SMILES
- CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C
- World Health Organisation international non-proprietary name
- artemether
via Wikidata · CC0