Structure via PubChem · Public domain (PubChem)
Avanafil
Sign in to saveAlso known as Spedra®, Stendra®, TA-1790, (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide
chemische Verbindung
Chemical data
- Formula
- C23H26ClN7O3
- Molecular weight
- 483.9 g/mol
- IUPAC name
- 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
- SMILES
- COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCC[C@H]4CO)Cl
- InChIKey
- WEAJZXNPAWBCOA-INIZCTEOSA-N
- XLogP
- 2.6
- Polar surface area
- 125 Ų
- H-bond donors
- 3
- H-bond acceptors
- 9
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2011
- Admin. routes
- oral
- Indications
- erectile dysfunction, kidney disease, Impotence
via ChEMBL · EBI
Wikidata facts
- Mass
- 483.178565
- Has use
- medication
Show 7 more facts
- significant drug interaction
- isosorbide dinitrate
- chemical formula
- C₂₃H₂₆ClN₇O₃
- canonical SMILES
- COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCCC4CO)Cl
- isomeric SMILES
- COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCC[C@H]4CO)Cl
- defined daily dose
- 0.1
- World Health Organisation international non-proprietary name
- avanafil
- Commons category
- Avanafil
via Wikidata · CC0
Article · Deutsch
Avanafil ist ein Arzneistoff aus der Gruppe der PDE-5-Hemmer, der in der Behandlung der erektilen Dysfunktion eingesetzt wird.
Abstract from DBpedia / Wikipedia · CC BY-SA