sertraline
Sign in to saveSertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. Although also having approval for post-traumatic stress disorder (PTSD), findings indicate it leads to only modest improvements in symptoms associated with this condition.
AI overview
Sertraline is an antidepressant medication, commonly sold as Zoloft, that works by affecting serotonin levels in the brain and is prescribed to treat conditions like depression, anxiety disorders, OCD, and panic disorder. It matters because it provides a widely-used treatment option for several mental health conditions, though research shows its effectiveness for PTSD is more limited.
AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 464389436
- Drug.image
- Sertraline.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Sertraline_3D_Ball-And-Stick.png
- Drug.image_class2
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- Drug.tradename
- Zoloft, Lustral, Setrona, others
- Drug.MedlinePlus
- a697048
- Drug.DailyMedID
- Sertraline
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- By mouth
- Drug.class
- Selective serotonin reuptake inhibitor (SSRI)
Article
34 sectionsContents
- Medical uses
- Depression
- Comparison with other antidepressants
- Depression in elderly
- Obsessive–compulsive disorder
- Panic disorder
- Other anxiety disorders
- Premenstrual dysphoric disorder
- Other indications
- Contraindications
- Side effects
- Sexual
- Suicide
- Therapeutic dosage
- Overdose
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Elimination
- Pharmacogenomics
- Chemistry
- History
- Society and culture
- Generic availability
- Brand names
- Interest during COVID-19 pandemic
- Research
- See also
- References
- External links
Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. Although also having approval for post-traumatic stress disorder (PTSD), findings indicate it leads to only modest improvements in symptoms associated with this condition.
The drug shares the common side effects and contraindications of other SSRIs, with high rates of nausea, diarrhea, headache, insomnia, mild sedation, dry mouth, and sexual dysfunction, but it appears not to lead to much weight gain, and its effects on cognitive performance are mild. Similar to other antidepressants, the use of sertraline for depression may be associated with a mildly elevated rate of suicidal thoughts in people under the age of 25 years old. It should not be used together with monoamine oxidase inhibitors (MAOIs): this combination may cause serotonin syndrome, which can be life-threatening in some cases. Sertraline taken during pregnancy is associated with an increase in congenital heart defects in newborns.