HBEGF
Sign in to saveAlso known as DTR, DTS, DTSF, HEGFL, heparin binding EGF like growth factor
protein-coding gene in humans that encodes heparin-binding EGF-like growth factor
In the Vinony graph
Within Vinony's link graph, HBEGF is referenced by 379 other articles, and connects out to PubMed, Ensembl genome database project and FGF8.
Vinony files it under Genes on human chromosome 5, Growth factors and Morphogens.
Its subject is documented across 6 Wikipedia language editions.
Gene data
HBEGF- Name
- heparin binding EGF like growth factor
- Type
- protein-coding
- Position
- 140,332,843–140,346,614 (−)
- Aliases
- DTR, DTS, DTSF, HB-EGF, HEGFL
- Ensembl
- ENSG00000113070
- RefSeq RNA
- NM_001945.3
- RefSeq protein
- NP_001936.1
Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
heparin binding EGF like growth factor
- Symbol
- HBEGF
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:140,332,843-140,346,614
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein HBEGF PDB 1xdt.png
Show 7 more facts
- HomoloGene ID
- 1466
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1839
- genomic end
- 140346603
- genomic start
- 139712428
- chromosome
- human chromosome 5
- cytogenetic location
- 5q31.3
via Wikidata · CC0