BAG2
Sign in to saveAlso known as BAG-2, dJ417I1.2, BCL2 associated athanogene 2, BAG cochaperone 2
BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to BAG2, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 6.
Vinony links it to 4 Wikipedia language editions.
Gene data
BAG2- Name
- BAG cochaperone 2
- Type
- protein-coding
- Aliases
- BAG-2, dJ417I1.2
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
BAG cochaperone 2
- Symbol
- BAG2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:57,172,272-57,189,833
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 31233
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9532
- genomic end
- 57054631
- genomic start
- 57037124
- chromosome
- human chromosome 6
- cytogenetic location
- 6p12.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- External links
- Further reading
BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene.
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Excerpted from Wikipedia’s “BAG2” article, available under the CC BY-SA 4.0 licence.