BAG5
Sign in to saveAlso known as BAG-5, BCL2 associated athanogene 5, BAG cochaperone 5, CMD2F
BAG family molecular chaperone regulator 5 is a protein that in humans is encoded by the BAG5 gene.
Gene data
BAG5- Name
- BAG cochaperone 5
- Type
- protein-coding
- Position
- 103,556,545–103,562,657 (−)
- Aliases
- BAG-5, CMD2F
- Ensembl
- ENSG00000166170
- RefSeq RNA
- NM_001015048.3, NM_001015049.5, NM_004873.4
- RefSeq protein
- NP_001015048.1, NP_001015049.2, NP_004864.1
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
- Image
- Protein BAG5 PDB 1ugo.png
Show 5 more facts
- HomoloGene ID
- 3584
- exact match
- identifiers.org/ncbigene/9529
- genomic end
- 103562657
- genomic start
- 103556545
- cytogenetic location
- 14q32.33
Sources (4)
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- References
- External links
- Further reading
BAG family molecular chaperone regulator 5 is a protein that in humans is encoded by the BAG5 gene.
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.