BAG5
Sign in to saveAlso known as BAG-5, BCL2 associated athanogene 5, BAG cochaperone 5, CMD2F
BAG family molecular chaperone regulator 5 is a protein that in humans is encoded by the BAG5 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to BAG5, and connects out to PubMed, human chromosome 14 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 14.
Vinony links it to 5 Wikipedia language editions.
Gene data
BAG5- Name
- BAG cochaperone 5
- Type
- protein-coding
- Position
- 103,556,545–103,576,759 (−)
- Aliases
- BAG-5, CMD2F
- Ensembl
- ENSG00000166170
- RefSeq RNA
- NM_001015048.3, NM_001015049.5, NM_004873.4
- RefSeq protein
- NP_001015048.1, NP_001015049.2, NP_004864.1
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
BAG cochaperone 5
- Symbol
- BAG5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:103,556,545-103,576,759
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein BAG5 PDB 1ugo.png
Show 7 more facts
- HomoloGene ID
- 3584
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9529
- genomic end
- 103562657
- genomic start
- 103556545
- chromosome
- human chromosome 14
- cytogenetic location
- 14q32.33
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
BAG family molecular chaperone regulator 5 is a protein that in humans is encoded by the BAG5 gene.
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.
Excerpted from Wikipedia’s “BAG5” article, available under the CC BY-SA 4.0 licence.