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EntityQ104529366· pop 10· linked from 19 articles

berotralstat

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Also known as Orladeyo, BCX7353

Berotralstat, sold under the brand name Orladeyo, is a medication used to prevent attacks of hereditary angioedema. Berotralstat is a plasma kallikrein inhibitor. It is taken by mouth.

Key facts

Drug.image
Berotralstat Structure.svg
Drug.image_class
skin-invert-image
Drug.tradename
Orladeyo
Drug.DailyMedID
Berotralstat
Drug.routes_of_administration
By mouth
Drug.class
Plasma kallikrein inhibitor
Drug.ATC_prefix
B06
Drug.ATC_suffix
AC06
Drug.legal_CA
Rx-only
Drug.legal_US
Rx-only
Drug.legal_EU
Rx-only
Drug.index2_label
as HCl
Drug.CAS_number
1809010-50-1
Drug.CAS_number2
1809010-52-3
Drug.PubChem
137528262
Drug.DrugBank
DB15982
Drug.ChemSpiderID
81368516
Drug.UNII
XZA0KB1BDQ

via Wikipedia infobox

Wikidata facts

Mass
562.210422332
Has use
medication
Show 3 more facts
canonical SMILES
C1CC1CNC(C2=CC(=C(C=C2)F)NC(=O)C3=CC(=NN3C4=CC=CC(=C4)CN)C(F)(F)F)C5=CC=CC(=C5)C#N
isomeric SMILES
C1CC1CN[C@@H](C2=CC(=C(C=C2)F)NC(=O)C3=CC(=NN3C4=CC=CC(=C4)CN)C(F)(F)F)C5=CC=CC(=C5)C#N
chemical formula
C₃₀H₂₆F₄N₆O

via Wikidata · CC0

~2 min read

Encyclopedic overview

7 sections
Contents
  • Medical uses
  • History
  • Society and culture
  • Legal status
  • Names
  • References
  • External links

Berotralstat, sold under the brand name Orladeyo, is a medication used to prevent attacks of hereditary angioedema. Berotralstat is a plasma kallikrein inhibitor. It is taken by mouth.

The most common side effects include abdominal pain, vomiting, diarrhea, back pain, and heartburn.

Excerpted from Wikipedia’s “berotralstat” article, available under the CC BY-SA 4.0 licence.

Available in 9 languages

via Wikidata sitelinks · CC0