Beta-2-microglobulin

Protein · UniProt

Beta-2-microglobulin

Gene

B2M

Organism

Homo sapiens (Human)

Length

119 aa

Molecular mass

13,715 Da

Evidence

1: Evidence at protein level

Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553)

• NACOMPLETED
  Comparison of the Removal of Uremic Toxins With Medium Cut-off and Super High-flux Vitamin E-coated DialyzersPoitiers University Hospital · NCT05610683
• COMPLETED
  The Effectiveness of Urine mtDNA and Beta 2-MG to Predict Acute Kidney Injury for Critically Ill Surgical PatientsWonju Severance Christian Hospital · NCT05458063
• COMPLETED
  Estimation of Kidney Function Through Combination of Renal Biomarkers in Blood and Urine of Healthy Infants and Children.University Hospital, Basel, Switzerland · NCT03751397
• UNKNOWN
  Evaluation of the Prognostic Impact of Decreased Serum beta2 Microglobulin in the First Year of Follow-up of Myeloproliferative Neoplasia (PRODIGE)University Hospital, Brest · NCT06553638
• NACOMPLETED
  Test of the Nipro ELISIO H Dialyzer in Different Dialysis Treatment ProceduresEXcorLab GmbH · NCT00735059
• NAUNKNOWN
  Controlled Internal Convection in Low Flow Hemodialysis of Dialysate: Removal of Beta-2-microglobulinUniversity Hospital, Caen · NCT05419271

via ClinicalTrials.gov