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ProteinQ420291· pop 22· linked from 119 articles

Also known as OVA

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up approximately 55% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein.

Key facts

Nonhuman protein.image
File:Ovalbumin.png
Nonhuman protein.caption
Structure of ovalbumin ()
Nonhuman protein.UniProt
P01012
Nonhuman protein.Organism
Gallus gallus

via Wikipedia infobox

Protein · UniProt

Ovalbumin

Gene
SERPINB14
Organism
Gallus gallus (Chicken)
Length
386 aa
Molecular mass
42,881 Da
Evidence
1: Evidence at protein level

Non-inhibitory serpin. Storage protein of egg white

3D-structureAcetylationAllergenCalciumDirect protein sequencingDisulfide bondGlycoproteinMetal-binding
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Swiss-Prot (reviewed) · via UniProt

Clinical Trials

7 registered

via ClinicalTrials.gov

Wikidata facts

Show 2 more facts
Commons category
Ovalbumin
NCI Thesaurus ID
C80992
Sources (2)

via Wikidata · CC0

~2 min read

Article

6 sections
Contents
  • Research
  • Structure
  • Change upon heating
  • See also
  • References
  • External links

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up approximately 55% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein.

== Research == Ovalbumin is an important protein in several different areas of research, including: general studies of protein structure and properties (because it is available in large quantities). studies of serpin structure and function (the fact that ovalbumin does not inhibit proteases means that by comparing its structure with that of inhibitory serpins, the structural characteristics required for inhibition can be determined). proteomics (chicken egg ovalbumin is commonly used as a molecular weight marker for calibrating electrophoresis gels). immunology (commonly used to stimulate an allergic reaction in test subjects; e.g., established model allergen for airway hyper-responsiveness, AHR).

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