File:Bruce_Beutler.jpg · Wikimedia Commons · See Wikimedia Commons
OverviewAI-generated
Bruce Alan Beutler is an American physician, geneticist, and immunologist born in Chicago in 1957. He works in the fields of immunology and physiology and serves as a university teacher. His professional affiliations include Scripps Research and The Rockefeller University. He is educated at the University of California, San Diego, and the Pritzker School of Medicine.
Beutler has received the Balzan Prize, the Albany Medical Center Prize, the Nobel Prize in Physiology or Medicine, and the William B. Coley Award. He is a member of the German Academy of Sciences Leopoldina, the National Academy of Sciences, and the American Academy of Arts and Sciences. His recognized works include *Immunology, phenotype first*, *Toll-like receptor family members and their ligands*, and *Tumor Necrosis Factors*. He resides in the United States and speaks English.
Synthesized by Vinony from 23 facts across 4 sources: Wikidata, Open Library, Nobel Prize, Vinony collections. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Person · Open Library
- Works
- 5
Top works
- Immunology, phenotype first
- Toll-like receptor family members and their ligands
- Toll-like receptor family members and their ligands
- Immunology, Phenotype First
- Tumor Necrosis Factors
via Open Library + Wikidata
Nobel Prize
- The Nobel Prize in Physiology or Medicine2011
“for their discoveries concerning the activation of innate immunity”
Shared · 1/4 portion
Wikidata facts
- Instance of
- human
- Given name
- Bruce
- Gender
- male
- Citizenship
- United States
- Place of birth
- Chicago
- Occupation
- scientist
- Employer
- The Rockefeller University
- Languages spoken
- English language
- Field of work
- physiology
- Official website
- www.utsouthwestern.edu/labs/beutler
- Image
- Nobel Prize 2011-Press Conference KI-DSC 7512.jpg
- Residence
- United States
Show 5 more facts
- Commons category
- Bruce Beutler
- date of birth
- 1957-12-29
- name in native language
- Bruce Alan Beutler
- P8168
- Xiao Xin
Sources (15)
via Wikidata · CC0
~27 min read
Encyclopedic overview
Bruce Alan Beutler (/ˈbɔɪtlər/ BOYT-lər; born December 29, 1957) is an American immunologist and geneticist. Together with Jules A. Hoffmann, he received one-half of the 2011 Nobel Prize in Physiology or Medicine, for "discoveries concerning the activation of innate immunity." Beutler discovered the long-elusive receptor for lipopolysaccharide (LPS; also known as endotoxin). He did so by identifying spontaneous mutations in the gene coding for mouse Toll-like receptor 4 (Tlr4) in two unrelated strains of LPS-refractory mice and proving they were responsible for that phenotype. Subsequently, and chiefly through the work of Shizuo Akira, other TLRs were shown to detect signature molecules of most infectious microbes, in each case triggering an innate immune response.
The other half of the Nobel Prize went to Ralph M. Steinman for "his discovery of the dendritic cell and its role in adaptive immunity."
Excerpted from Wikipedia’s “Bruce Beutler” article, available under the CC BY-SA 4.0 licence.