BTAF1

Also known as MOT1, TAF(II)170, TAF172, TAFII170, B-TFIID TATA-box binding protein associated factor 1

TATA-binding protein-associated factor 172 is a protein that in humans is encoded by the BTAF1 gene.

Gene data

BTAF1

Name: B-TFIID TATA-box binding protein associated factor 1
Type: protein-coding
Position: 91,923,770–92,031,437 (+)
Aliases: MOT1, TAF(II)170, TAF172, TAFII170
Ensembl: ENSG00000095564
RefSeq RNA: NM_003972.3, NR_165090.1, NR_165091.1, NR_165092.1, NR_165093.1
RefSeq protein: NP_003963.1, XP_011538628.1, XP_011538629.1, XP_011538630.1, XP_016872366.1

This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011].