bulevirtide
Sign in to saveAlso known as Hepcludex, Myrcludex B
Bulevirtide, sold under the brand name Hepcludex, is an antiviral medication used for the treatment of chronic hepatitis D (in the presence of hepatitis B).
In the Vinony graph
Vinony's link graph records 104 inbound references to bulevirtide, and connects out to antiviral drug, influenza and digital object identifier.
It is catalogued under topics including Anti–RNA virus drugs, Chemicals using indexlabels and Drugs with non-standard legal status.
Vinony links it to 4 Wikipedia language editions.
Chemical data
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Protein
- Indications
- hepatitis D virus infection, viral disease, hepatitis B virus infection, chronic hepatitis
via ChEMBL · EBI
Clinical Trials
23 registered- PHASE2COMPLETEDStudy to Assess Efficacy and Safety of Bulevirtide in Combination With Pegylated Interferon Alfa-2a in Participants With Chronic Hepatitis Delta (CHD)Gilead Sciences · NCT03852433
- PHASE3RECRUITINGA Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With BulevirtideVir Biotechnology, Inc. · NCT07128550
- ACTIVE_NOT_RECRUITINGImprovement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D)Hannover Medical School · NCT04863703
- PHASE2ACTIVE_NOT_RECRUITINGA Study to Evaluate Tobevibart+Elebsiran Versus Bulevirtide in Chronic HDV InfectionVir Biotechnology, Inc. · NCT07142811
- COMPLETEDAssessment of Response and Safety of Bulevirtide Treatment in Patients With Chronic Delta Virus InfectionUniversity of Molise · NCT07116044
- RECRUITINGChanges in Bile Acids and Microbiota in Patients With Hepatitis D Treated With BulvertideFondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT07429864
Wikidata facts
Show 1 more fact
- Commons category
- Bulevirtide
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Medical uses
- Pharmacology
- Mechanism of action
- Structural formula
- References
Bulevirtide, sold under the brand name Hepcludex, is an antiviral medication used for the treatment of chronic hepatitis D (in the presence of hepatitis B).
The most common side effects include raised levels of bile salts in the blood and reactions at the site of injection.
Excerpted from Wikipedia’s “bulevirtide” article, available under the CC BY-SA 4.0 licence.