dasabuvir
Sign in to saveAlso known as ABT-333, N-{6-[3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide, ABT 333, sodium 3-(3-tert-butyl-4-methoxy-5-{6 [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ide hydrate (1:1:1)
Dasabuvir, sold under the brand name Exviera, is an antiviral medication for the treatment of hepatitis C. It is often used together with the combination medication ombitasvir/paritaprevir/ritonavir specifically for hepatitis C virus (HCV) type 1. Ribavirin may also additionally be used. These combinations result in a cure in more than 90% of people. It is taken by mouth.
In the Vinony graph
Within Vinony's link graph, dasabuvir is referenced by 105 other articles, and connects out to antiviral drug, ombitasvir/paritaprevir/ritonavir and RNA dependent RNA polymerase, hepatitis C virus.
It is catalogued under topics including Chemicals using indexlabels, Drugs with non-standard legal status and ECHA InfoCard ID from Wikidata.
Its subject is documented across 15 Wikipedia language editions.
Key facts
- Drug.UNII
- DE54EQW8T1
- Drug.image
- Dasabuvir.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Exviera, Viekira Pak, Viekira XR
- Drug.Drugs.com
- Viekira Pak Dasabuvir
- Drug.MedlinePlus
- a616040
- Drug.DailyMedID
- Dasabuvir
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- J05
- Drug.ATC_suffix
- AP09
- Drug.legal_AU
- S4
- Drug.legal_US
- Rx-only
- Drug.legal_US_comment
- co-packaged with ombitasvir/paritaprevir/ritonavir (Viekira Pak)
- Drug.legal_EU
- Rx-only
- Drug.index2_label
- as salt
- Drug.CAS_number
- 1132935-63-7
- Drug.PubChem
- 56640146
- Drug.ChemSpiderID
- 29776744
via Wikipedia infobox
Wikidata facts
- Mass
- 493.167142
Show 3 more facts
- chemical formula
- C₂₆H₂₇N₃O₅S
- canonical SMILES
- CC(C)(C)C1=C(C(=CC(=C1)N2C=CC(=O)NC2=O)C3=CC4=C(C=C3)C=C(C=C4)NS(=O)(=O)C)OC
- World Health Organisation international non-proprietary name
- dasabuvir
Sources (5)
via Wikidata · CC0
~7 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Contraindications
- Adverse effects
- Mechanism of action
- History
- Administration and storage
- References
{{Infobox drug | drug_name = | image = Dasabuvir.svg | image_class = skin-invert-image | alt = | caption =
| tradename = Exviera, Viekira Pak, Viekira XR | Drugs.com = Viekira Pak Dasabuvir | MedlinePlus = a616040 | DailyMedID = Dasabuvir | pregnancy_AU = | pregnancy_category= | routes_of_administration = By mouth | ATC_prefix = J05 | ATC_suffix = AP09
Excerpted from Wikipedia’s “dasabuvir” article, available under the CC BY-SA 4.0 licence.