C3-convertase
Sign in to savethumb|right|270px|The classical and alternative complement pathways. thumb|right|270px|Complement-pathways. C3 convertase (C4bC2b, formerly C4b2a) belongs to family of serine proteases and is necessary in innate immunity as a part of the complement system which eventuate in opsonisation of particles, release of inflammatory peptides, C5 convertase formation and cell lysis.
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- EC enzyme number
- 3.4.21.43
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Article
7 sectionsContents
- Formation
- Alternative pathway
- Classical and lectin pathways
- Regulation
- Location on chromosome
- References
- External links
thumb|right|270px|The classical and alternative complement pathways. thumb|right|270px|Complement-pathways. C3 convertase (C4bC2b, formerly C4b2a) belongs to family of serine proteases and is necessary in innate immunity as a part of the complement system which eventuate in opsonisation of particles, release of inflammatory peptides, C5 convertase formation and cell lysis.
C3 convertase can be used to refer to the form produced in the alternative pathway (C3bBb) or the classical and lectin pathways (C4bC2b, formerly C4b2a). Once formed, both C3 convertases will catalyze the proteolytic cleavage of C3 into C3a and C3b (hence the name "C3-convertase").