canagliflozin
Sign in to saveAlso known as JNJ-28431754, TA-7284, 1-(Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene, canagliflozin anhydrous, Canagliflozin anhydrous
Canagliflozin, sold under the brand name Invokana among others, is a medication used to treat type 2 diabetes. It is used together with exercise and diet. It is not recommended in type 1 diabetes. It is taken by mouth.
Key facts
- Drug.legal_EU
- Rx-only
- Drug.legal_status
- Rx-only
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 416773181
- Drug.image
- Canagliflozin structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.tradename
- Invokana, Sulisent, Prominad, others
- Drug.MedlinePlus
- a613033
- Drug.DailyMedID
- Canagliflozin
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- By mouth
- Drug.class
- SGLT2 inhibitor
- Drug.ATC_prefix
- A10
- Drug.ATC_suffix
- BK02
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
via Wikipedia infobox
Research
2,345 papers- Canagliflozin and Heart Failure in Type 2 Diabetes Mellitus: Results From the CANVAS Program.Circulation · 2018
- Canagliflozin Mitigates Diabetic Cardiomyopathy through Enhanced PINK1-Parkin Mitophagy.International journal of molecular sciences · 2024
- Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes.The New England journal of medicine · 2017
- Canagliflozin and renal outcomes in type 2 diabetes: results from the CANVAS Program randomised clinical trials.The lancet. Diabetes & endocrinology · 2018
- Canagliflozin and Amputation Risk: Evidence So Far.The international journal of lower extremity wounds · 2020
via PubMed
Wikidata facts
- Mass
- 444.141
- Has use
- medication
Show 5 more facts
- chemical formula
- C₂₄H₂₅FO₅S
- canonical SMILES
- CC1=C(C=C(C=C1)C2C(C(C(C(O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F
- isomeric SMILES
- CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F
- subject has role
- gliflozins
- Commons category
- Canagliflozin
via Wikidata · CC0
~13 min read
Encyclopedic overview
10 sectionsContents
- Medical uses
- Contraindications
- Adverse effects
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- History
- See also
- References
{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 416773181 | image = Canagliflozin structure.svg | image_class = skin-invert-image | width = 200 | alt = | caption =
| pronounce = | tradename = Invokana, Sulisent, Prominad, others | Drugs.com = | MedlinePlus = a613033 | DailyMedID = Canagliflozin | pregnancy_AU = C | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = By mouth | class = SGLT2 inhibitor | ATC_prefix = A10 | ATC_suffix = BK02 | ATC_supplemental =
Excerpted from Wikipedia’s “canagliflozin” article, available under the CC BY-SA 4.0 licence.
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