Structure via PubChem · Public domain (PubChem)
bexagliflozin
Sign in to saveBexagliflozin, sold under the brand name Brenzavvy, is an antidiabetic medication used to improve glycemic control in adults with type 2 diabetes. It is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that is taken by mouth.
Chemical data
- Formula
- C24H29ClO7
- Molecular weight
- 464.9 g/mol
- IUPAC name
- (2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-(2-cyclopropyloxyethoxy)phenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
- SMILES
- C1CC1OCCOC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl
- InChIKey
- BTCRKOKVYTVOLU-SJSRKZJXSA-N
- XLogP
- 2.4
- Polar surface area
- 109 Ų
- H-bond donors
- 4
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2023
- Admin. routes
- oral
- Indications
- diabetes mellitus, essential hypertension, type 2 diabetes mellitus
via ChEMBL · EBI
Wikidata facts
- Instance of
- gliflozins
- Subclass of
- chemical compound
- Mass
- 464.16
Show 5 more facts
- canonical SMILES
- C1CC1OCCOC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl
- chemical formula
- C₂₄H₂₉ClO₇
- isomeric SMILES
- C1CC1OCCOC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl
- subject has role
- veterinary drug
- Commons category
- Bexagliflozin
Sources (1)
via Wikidata · CC0
~6 min read
Encyclopedic overview
10 sectionsContents
- Medical uses
- Adverse effects
- History
- Society and culture
- Legal status
- Research
- Veterinary uses
- References
- Further reading
- External links
{{Infobox drug | image = Bexagliflozin structure.svg | image_class = skin-invert-image | width = 325 | alt = | caption =
| pronounce = | tradename = Brenzavvy, Bexacat | Drugs.com = | MedlinePlus = a623027 | DailyMedID = Bexagliflozin | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = | ATC_prefix = A10 | ATC_suffix = BK08 | ATC_supplemental =
Excerpted from Wikipedia’s “bexagliflozin” article, available under the CC BY-SA 4.0 licence.