CD2AP

Also known as CMS, CD2-associated protein, CD2 associated protein

CD2-associated protein is a protein that in humans is encoded by the CD2AP gene.

In the Vinony graph

Vinony's link graph records 14 inbound references to CD2AP, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 6.

Vinony links it to 7 Wikipedia language editions.

Gene data

CD2AP

Name: CD2 associated protein
Type: protein-coding
Position: 47,477,732–47,627,275 (+)
Aliases: CMS
Ensembl: ENSG00000198087
RefSeq RNA: NM_012120.3, XM_005248976.2, XM_011514449.3, XM_017010641.2, XM_054354982.1
RefSeq protein: NP_036252.1, XP_005249033.1, XP_011512751.1, XP_016866130.1, XP_054210957.1

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008].