CD2BP2
Sign in to saveAlso known as FWP010, LIN1, PPP1R59, Snu40, U5-52K, CD2 (cytoplasmic tail) binding protein 2, CD2 cytoplasmic tail binding protein 2
CD2 antigen cytoplasmic tail-binding protein 2 is a protein that in humans is encoded by the CD2BP2 gene.
Gene data
CD2BP2- Name
- CD2 cytoplasmic tail binding protein 2
- Type
- protein-coding
- Position
- 30,350,767–30,355,308 (−)
- Aliases
- FWP010, LIN1, PPP1R59, Snu40, U5-52K
- Ensembl
- ENSG00000169217
- RefSeq RNA
- NM_001243646.2, NM_006110.3
- RefSeq protein
- NP_001230575.1, NP_006101.1
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Wikidata facts
- Image
- Protein CD2BP2 PDB 1gyf.png
Show 5 more facts
- HomoloGene ID
- 4455
- exact match
- identifiers.org/ncbigene/10421
- genomic end
- 30355308
- genomic start
- 30350773
- cytogenetic location
- 16p11.2
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Interactions
- References
- Further reading
- External links
CD2 antigen cytoplasmic tail-binding protein 2 is a protein that in humans is encoded by the CD2BP2 gene.
==Interactions== CD2BP2 has been shown to interact with CD2.