CDC20

Also known as CDC20A, bA276H19.3, p55CDC, cell division cycle 20

gène de l'espèce Homo sapiens

In the Vinony graph

Vinony's link graph records 32 inbound references to CDC20, and connects out to PubMed, Ensembl genome database project and International Standard Book Number.

It is catalogued under the topic Genes on human chromosome 1.

Vinony links it to 7 Wikipedia language editions.

Gene data

CDC20

Name: cell division cycle 20
Type: protein-coding
Position: 43,358,907–43,363,212 (+)
Aliases: CDC20A, OOMD14, OZEMA14, bA276H19.3, p55CDC
Ensembl: ENSG00000117399
RefSeq RNA: NM_001255.3
RefSeq protein: NP_001246.2

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

mitotic spindle assembly checkpoint signaling regulation of mitotic cell cycle positive regulation of cell population proliferation protein ubiquitination anaphase-promoting complex-dependent catabolic process anaphase-promoting complex-dependent catabolic process anaphase-promoting complex-dependent catabolic process positive regulation of synaptic plasticity

Molecular function

protein binding anaphase-promoting complex binding anaphase-promoting complex binding anaphase-promoting complex binding histone deacetylase binding ubiquitin-protein transferase activator activity ubiquitin-like ligase-substrate adaptor activity ubiquitin ligase activator activity

Cellular component

kinetochore kinetochore spindle pole nucleoplasm anaphase-promoting complex anaphase-promoting complex anaphase-promoting complex anaphase-promoting complex

Pathways

Cell cycle - Homo sapiens (human)Oocyte meiosis - Homo sapiens (human)Ubiquitin mediated proteolysis - Homo sapiens (human)Human T-cell leukemia virus 1 infection - Homo sapiens (human)Viral carcinogenesis - Homo sapiens (human)Adaptive Immune System Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components Amplification of signal from the kinetochores Inactivation of APC/C via direct inhibition of the APC/C complex Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal

via MyGene.info

Gene · Ensembl

cell division cycle 20

Symbol: CDC20
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:43,358,907-43,363,212
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: CDC20.png

Show 8 more facts

exact match: identifiers.org/ncbigene/991
HomoloGene ID: 37459
found in taxon: Homo sapiens
genomic end: 43828874
genomic start: 43358981
chromosome: human chromosome 1
cytogenetic location: 1p34.2
expressed in: trabecular bone

Sources (6)

via Wikidata · CC0

Article · Français

Cdc20 (cell division cycle protein 20 homolog) est une protéine essentielle dans la régulation de la division cellulaire et plusieurs autres processus. Elle est l'une des protéines qui régule le cycle cellulaire lors de la promotion de l'anaphase. Cdc20 est encodée par le gêne CDC20 (localisé en 1p34.2 dans le génome humain).

Abstract from DBpedia / Wikipedia · CC BY-SA