CDKN2D

Name

cyclin dependent kinase inhibitor 2D

Type

protein-coding

Position

10,566,460–10,569,059 (−)

Aliases

INK4D, p19, p19-INK4D

Ensembl

ENSG00000129355

RefSeq RNA

NM_001800.4, NM_079421.3

RefSeq protein

NP_001791.1, NP_524145.1

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

cyclin dependent kinase inhibitor 2D

Symbol

CDKN2D

Biotype

Protein coding

Organism

Homo sapiens

Location

19:10,566,460-10,569,059

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein CDKN2D PDB 1bd8.png

via Wikidata · CC0